Iron, Atherosclerosis, and Ischemic Heart Disease
نویسندگان
چکیده
منابع مشابه
Iron, atherosclerosis, and ischemic heart disease.
OBJECTIVE To review the epidemiological and experimental data concerning iron and the development of atherosclerosis and ischemic heart disease. DATA SOURCES The English-language literature was searched from 1981 through 1998 manually and using MEDLINE and Current Contents. Important references in the articles that were found were also included in this review. RESULTS There is growing epide...
متن کاملIron, Atherosclerosis, and Ischemic Heart Disease
Results: There is growing epidemiological evidence for a relationship between iron levels and cardiovascular disease. Some experimental data support the role of iron in the process of lipid peroxidation, the first step in the formation of atherosclerotic lesions. Macrophages and endothelial cells are involved in this process, but the exact mechanism and the sites of the interactions between the...
متن کاملIschemic heart disease, atherosclerosis, and longevity.
IN THE LATE 1940's Duff and McMillan' 2 made the remarkable observation that alloxan-diabetic rabbits developed equal or higher blood cholesterol levels, but markedly less atherosclerosis, than did nondiabetic rabbits fed an equivalent high-cholesterol diet. From the excessive visible lipemia characteristic of the alloxan-diabetic rabbits in this experiment, Duff and McMillan surmised that the ...
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چکیده مقدمه: بیماری های ایسکمیک قلب با ویژگی کاهش خون رسانی به ماهیچه قلب، به علت بیماری های عروق کرونر از جمله آترواسکلروز ایجاد می شود. از افزایش فعالیت گزانتین اکسیداز نیز منجر به عدم کارایی عروق در خون رسانی به عضله ی قلب و ایجاد انواع ایسکمی و آسیبهای بافتی و عروقی می شود. به نظر می رسد، داروهای مهارکننده گزانتین اکسیداز از طریق افزایش شرب بافتی در بهبود علائم بیماری های ایسکمیک قلب موثر ...
Obstructive coronary atherosclerosis and ischemic heart disease: an elusive link!
In the current pathophysiological model of chronic ischemic heart disease (IHD), myocardial ischemia and exertional angina are caused by obstructive atherosclerotic plaque, and the clinical management of IHD is centered on the identification and removal of the stenosis. Although this approach has been in place for years, several lines of evidence, including poor prognostic impact, suggest that ...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 1999
ISSN: 0003-9926
DOI: 10.1001/archinte.159.14.1542